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Karp's Cell and Molecular Biology

Karp's Cell and Molecular Biology 9th Edition

By: Gerald Karp Janet Iwasa Wallace Marshall
ISBN-10: 1119598249
/ ISBN-13: 9781119598169
Edition: 9th Edition
Language: English
				
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CHAPTER 1: Introduction to the Study of Cell and Molecular Biology

    • 1.1 The Discovery of Cells
    • 1.2 Basic Properties of Cells
    • 1.3 Two Fundamentally Different Classes of Cells
    • 1.4 Viruses and Viroids
    • 1.5 Green Cells: Volvox, an Experiment in Multicellularity
    • 1.6 Engineering Linkage: Tissue Engineering
    • Analytic Questions

CHAPTER 2: The Chemical Basis of Life

    • 2.1 Covalent Bonds
    • 2.2 Engineering Linkage: Radionuclides for Imaging and Treatment
    • 2.3 Noncovalent Bonds
    • 2.4 Acids, Bases, and Buffers
    • 2.5 The Nature of Biological Molecules
    • 2.6 Green Cells: Chemical Fertilizers
    • 2.7 Four Types of Biological Molecules
    • 2.8 The Formation of Complex Macromolecular Structures
    • Analytic Questions

CHAPTER 3: Bioenergetics, Enzymes, and Metabolism

    • 3.1 Bioenergetics
    • 3.2 Enzymes as Biological Catalysts
    • 3.3 Metabolism
    • 3.4 Green Cells: Regulation of Metabolism by the Light/Dark Cycle
    • 3.5 Engineering Linkage: Using Metabolism to Image Tumors
    • Analytic Questions

CHAPTER 4: The Structure and Function of the Plasma Membrane

    • 4.1 Introduction to the Plasma Membrane
    • 4.2 The Chemical Composition of Membranes
    • 4.3 Membrane Proteins
    • 4.4 Membrane Lipids and Membrane Fluidity
    • 4.5 The Dynamic Nature of the Plasma Membrane
    • 4.6 The Movement of Substances across Cell Membranes
    • 4.7 Membrane Potentials and Nerve Impulses
    • 4.8 Green Cells: Electrical Signaling in Plants
    • 4.9 Engineering Linkage: Neurotechnology
    • Analytic Questions

CHAPTER 5: Aerobic Respiration and the Mitochondrion

    • 5.1 Mitochondrial Structure and Function
    • 5.2 Aerobic Metabolism in the Mitochondrion
    • 5.3 The Role of Mitochondria in the Formation of ATP
    • 5.4 Engineering Linkage: Measuring Blood Oxygen
    • 5.5 Establishment of a Proton-Motive Force
    • 5.6 The Machinery for ATP Formation
    • 5.7 Peroxisomes
    • 5.8 Green Cells: Glyoxysomes
    • Analytic Questions

CHAPTER 6: Photosynthesis and the Chloroplast

    • 6.1 The Origin of Photosynthesis
    • 6.2 Chloroplast Structure
    • 6.3 An Overview of Photosynthetic Metabolism
    • 6.4 The Absorption of Light
    • 6.5 Green Cells: Chromoplasts
    • 6.6 Photosynthetic Units and Reaction Centers
    • 6.7 Photophosphorylation
    • 6.8 Carbon Dioxide Fixation and the Synthesis of Carbohydrate
    • 6.9 Engineering Linkage: Photodynamic Therapy
    • Analytic Questions

CHAPTER 7: Interactions Between Cells and Their Environment

    • 7.1 Extracellular Interactions
    • 7.2 Engineering Linkage: Organoids
    • 7.3 Interactions of Cells with Extracellular Materials
    • 7.4 Interactions of Cells with Other Cells
    • 7.5 Tight Junctions: Sealing the Extracellular Space
    • 7.6 Intercellular Communication
    • 7.7 Cell Walls
    • 7.8 Green Cells: Cell Walls and Plant Terrestrialization
    • Analytic Questions

CHAPTER 8: Cytoplasmic Membrane Systems: Structure, Function, and Membrane Traff…

    • 8.1 An Overview of the Endomembrane System
    • 8.2 A Few Approaches to the Study of Endomembranes
    • 8.3 The Endoplasmic Reticulum
    • 8.4 The Golgi Complex
    • 8.5 Types of Vesicle Transport
    • 8.6 Engineering Linkage: Extracellular Vesicles for Drug Delivery
    • 8.7 Lysosomes
    • 8.8 Green Cells: Plant Cell Vacuoles
    • 8.9 The Endocytic Pathway: Moving Membrane and Materials into the Cell Interior
    • 8.10 Posttranslational Uptake of Proteins by Peroxisomes, Mitochondria, and Chlo…
    • Analytic Questions

CHAPTER 9: The Cytoskeleton and Cell Motility

    • 9.1 Overview of the Major Functions of the Cytoskeleton
    • 9.2 Structure and Function of Microtubules
    • 9.3 Green Cells: Why the Woodbine Twineth
    • 9.4 Motor Proteins: Kinesins and Dyneins
    • 9.5 Microtubule-Organizing Centers (MTOCs)
    • 9.6 Structure and Function of Cilia and Flagella
    • 9.7 Intermediate Filaments
    • 9.8 Actin and Myosin
    • 9.9 Muscle Organization and Contraction
    • 9.10 Engineering Linkage: Muscle Biomechanics
    • 9.11 Actin-Binding Proteins
    • 9.12 Cellular Motility
    • 9.13 The Bacterial Cytoskeleton
    • Analytic Questions

CHAPTER 10: The Nature of the Gene and the Genome

    • 10.1 The Concept of a Gene as a Unit of Inheritance
    • 10.2 The Discovery of Chromosomes
    • 10.3 Chromosomes as the Carriers of Genetic Information
    • 10.4 The Chemical Nature of the Gene
    • 10.5 The Complexity of the Genome
    • 10.6 The Stability of the Genome
    • 10.7 Sequencing Genomes: The Footprints of Biological Evolution
    • 10.8 Engineering Linkage: Engineering Genomes
    • 10.9 The Genetic Basis of “Being Human”
    • 10.10 Green Cells: Gene Transfer by Agrobacterium tumefaciens
    • Analytic Questions

CHAPTER 11: The Central Dogma: DNA to RNA to Protein

    • 11.1 The Relationships among Genes, Proteins, and RNAs
    • 11.2 An Overview of Transcription in Both Prokaryotic and Eukaryotic Cells
    • 11.3 Synthesis and Processing of Eukaryotic Ribosomal and Transfer RNAs
    • 11.4 Synthesis and Structure of Eukaryotic Messenger RNAs
    • 11.5 Small Regulatory RNAs and RNA Silencing Pathways
    • 11.6 Green Cells: Long-Range siRNA Movement
    • 11.7 CRISPR and Other Noncoding RNAs
    • 11.8 Encoding Genetic Information
    • 11.9 Decoding the Codons: The Role of Transfer RNAs
    • 11.10 Translating Genetic Information
    • 11.11 Engineering Linkage: DNA Origami
    • Analytic Questions

CHAPTER 12: Control of Gene Expression

    • 12.1 Control of Gene Expression in Bacteria
    • 12.2 Engineering Linkage: Building Digital Logic with Genes
    • 12.3 Structure of the Nuclear Envelope
    • 12.4 Chromosomes and Chromatin
    • 12.5 The Nucleus as an Organized Organelle
    • 12.6 An Overview of Gene Regulation in Eukaryotes
    • 12.7 Transcriptional Control
    • 12.8 Green Cells: The ABC Model and MADS Domain Transcription Factors
    • 12.9 RNA Processing Control
    • 12.10 Translational Control
    • 12.11 Posttranslational Control: Determining Protein Stability
    • Analytic Questions

CHAPTER 13: DNA Replication and Repair

    • 13.1 DNA Replication
    • 13.2 DNA Replication in Bacterial Cells
    • 13.3 The Structure and Functions of DNA Polymerases
    • 13.4 Replication in Viruses
    • 13.5 Engineering Linkage: Storing Data in DNA
    • 13.6 DNA Replication in Eukaryotic Cells
    • 13.7 DNA Repair
    • 13.8 Green Cells: Gamma Gardens
    • 13.9 Between Replication and Repair
    • Analytic Questions

CHAPTER 14: Cell Division

    • 14.1 The Cell Cycle
    • 14.2 M Phase: Mitosis and Cytokinesis
    • 14.3 Engineering Linkage: The Role of Membrane Tension in Cell Division
    • 14.4 Green Cells: Unique Aspects of Plant Cell Division
    • 14.5 Meiosis
    • Analytic Questions

CHAPTER 15: Cell Signaling and Signal Transduction: Communication between Cells

    • 15.1 The Basic Elements of Cell Signaling Systems
    • 15.2 A Survey of Extracellular Messages and Their Receptors
    • 15.3 G Protein-Coupled Receptors and Their Second Messengers
    • 15.4 Engineering Linkage: Biosensors in Medicine and Biology
    • 15.5 Protein-Tyrosine Phosphorylation as a Mechanism for Signal Transduction
    • 15.6 Green Cells: Auxin Signaling
    • 15.7 The Role of Calcium as an Intracellular Messenger
    • 15.8 Convergence, Divergence, and Cross-Talk among Different Signaling Pathways
    • 15.9 The Role of NO as an Intracellular Messenger
    • 15.10 Apoptosis (Programmed Cell Death)
    • Analytic Questions

CHAPTER 16: Cancer

    • 16.1 Basic Properties of a Cancer Cell
    • 16.2 The Causes of Cancer
    • 16.3 Cancer: A Genetic Disorder
    • 16.4 Engineering Linkage: Therapeutic Radiation
    • 16.5 Green Cells: Plant-Based Chemotherapies
    • 16.6 Strategies for Combating Cancer

CHAPTER 17: The Immune Response

    • 17.1 An Overview of the Immune Response
    • 17.2 Green Cells: The Plant Immune System
    • 17.3 The Clonal Selection Theory as It Applies to B Cells
    • 17.4 T Lymphocytes: Activation and Mechanism of Action
    • 17.5 Selected Topics on the Cellular and Molecular Basis of Immunity
    • 17.6 Engineering Linkage: Adoptive T-Cell Therapy
    • 17.7 Signal Transduction Pathways in Lymphocyte Activation

CHAPTER 18: Techniques in Cell and Molecular Biology

    • 18.1 The Light Microscope
    • 18.2 Transmission Electron Microscopy
    • 18.3 Scanning Electron and Atomic Force Microscopy
    • 18.4 The Use of Radioisotopes
    • 18.5 Cell Culture
    • 18.6 The Fractionation of a Cell’s Contents by Differential Centrifugation
    • 18.7 Isolation, Purification, and Fractionation of Proteins
    • 18.8 Determining the Structure of Proteins and Multisubunit Complexes
    • 18.9 Fractionation of Nucleic Acids
    • 18.10 Nucleic Acid Hybridization
    • 18.11 Chemical Synthesis of DNA
    • 18.12 Recombinant DNA Technology
    • 18.13 Enzymatic Amplification of DNA by PCR
    • 18.14 DNA Sequencing
    • 18.15 DNA Libraries
    • 18.16 DNA Transfer into Eukaryotic Cells and Mammalian Embryos
    • 18.17 Gene Editing and Silencing
    • 18.18 The Use of Antibodies

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